SqlAlchemy is an object-oriented DB API for Python.
SQLAlchemy is the Python SQL toolkit and Object Relational Mapper that gives application developers the full power and flexibility of SQL.
It provides a full suite of well known enterprise-level persistence patterns, designed for efficient and high-performing database access, adapted into a simple and Pythonic domain language.
We talked a bit about adopting it for Trac's DB abstraction layer, eventually replacing our home grown db layer.
Some experimental work has started in source:sandbox/Attic/sqlalchemy-ng